Latest News: Technology |  Celebrity |  Movies |  Apple |  Cars |  Business |  Sports |  TV Shows |  Geek

Trending

Filed under: News | Misc

 

Functional Human Liver Tissue Successfully Grown from Stem Cells

Scientists have been able to grow functional human liver tissue and transplant it in ordinary mice. Stem cells were used in the process which was successfully carried out by Japanese scientists in lab settings.

Jul 4 2013, 5:55am CDT | by

1 Updates
Functional Human Liver Tissue Successfully Grown from Stem Cells
 
 

YouTube Videos Comments

Full Story

Functional Human Liver Tissue Successfully Grown from Stem Cells

Functional Human Liver Tissue Successfully Grown from Stem Cells

Stem cells were employed in an effort to create human liver tissue. The end products were much smaller than full-fledged human livers. Nevertheless, they functioned perfectly well when transplanted in mice. According to the Smithsonian , the miniature livers were attached to the circulatory system of the mice. They functioned like normal livers clearing away the toxins from the blood. This is the first time the world has seen a really effective organ made by humans in the laboratory. Until now all attempts had yielded no results. The whole process was possible courtesy of stem cell research, which is on the leading edge of medical miracles. Instead of relying on organ donations, stem cells are used to grow the organs in a cultural medium. Already there is talk of the re-grown liver tissue being capable of restoring 30% of the liver function in a human being. But the technology is still in its infancy. It will take over a decade for it to be fine-tuned to fit human physical requirements.

Scientists at Yokohama City University took some samples of human skin cells. These were then treated chemically and grown into early-phase liver cells. Termed pluripotent stem cells, these samples had other human cells from the veins of umbilical cords added to them. The researchers were flabbergasted when they saw the tissues slowly and steadily forming into liver-like organs. The whole process resembled the growth of a liver in a fetus.

The growth continued for the span of two months. At the end of this duration they were transplanted into the internal biological systems of lab mice. Soon enough they began to function with perfect precision. When certain drugs were given to these mice the human transplants filtered the toxins from these medications. Then a potentially lethal drug was given to the mice to test the consequences of the experiment even further. The control group died within ten days. But the mice with the human transplants lived 40 days before dying.

This is a significant find. The next step would be to test drive the liver tissue in human beings. Of course, there is a huge difference between a small liver that fits inside a rat and a human-sized liver. The liver is the largest organ of the body and making one fit for a human being would take a lot of work. Furthermore, the chances of rejection by the host organism may lead to the development of certain drugs that allow acceptance of the liver tissue. A lot needs to be accomplished yet and it is too early to be jumping to any conclusions.

Watch Video of the Experiment.

Image Credit: Getty Images

 

iPad Air Giveaway. Win a free iPad Air.

You Might Also Like

Updates


Sponsored Update


Advertisement


More From the Web

Shopping Deals

 
 
 

<a href="/latest_stories/all/all/20" rel="author">Sumayah Aamir</a>
Sumayah Aamir (Google+) has deep experience in analyzing the latest trends.

 

 

Comments

blog comments powered by Disqus

Latest stories

Bill Belichick Offers No Comment on Aaron Hernandez Texts
Bill Belichick Offers No Comment on Aaron Hernandez Texts
New England Patriots head coach Bill Belichick did not offer any comment on questions regarding his text messages with former tight end Aaron Hernandez, who is charged with the murder of three individuals.
 
 
Jamaal Charles Agrees to $18M Extension with Kansas City Chiefs
Jamaal Charles Agrees to $18M Extension with Kansas City Chiefs
Running back Jamaal Charles agreed to an $18 million contract extension including an extra $5.1 million over the next two seasons with the Kansas City Chiefs on July 23.
 
 
Batman Day: Brad Meltzer On Why Batman&#039;s &#039;Cultural Shield&#039; Protects Us All
Batman Day: Brad Meltzer On Why Batman's 'Cultural Shield' Protects Us All
July 24, 2014, marks Batman Day for DC Comics. And writer Brad Meltzer tells why Batman's impact is so important.
 
 
Fat Shaming &quot;530 Fatties&quot; Facebook Page Reminds Society Of Bad Behavior
Fat Shaming "530 Fatties" Facebook Page Reminds Society Of Bad Behavior
Facebook Page "530 Fatties" openly mocks overweight people around Sacramento and the 530 area code. But it's certainly not the first time that people have faced body image criticism.
 
 
 

About the Geek Mind


Read more about The Geek Mind.