Testosterone Treatment Provides Cardiovascular Benefits To Veterans

Posted: Aug 11 2015, 6:55am CDT | by , in News | Latest Science News


Testosterone Treatment Provides Cardiovascular Benefits to Veterans
Credit: Michael Moody
  • Testosterone Therapy is Ideal for Older Males with Cardiac Issues

It was found that testosterone therapy is ideal for older males. This is especially so in case of those having cardiac issues.

Testosterone Replacement Therapy (TRT) has a salubrious effect on older males. That is if they suffered from cardiovascular difficulties, myocardial infarction or stroke. They will benefit via TRT. When normal levels of testosterone got reached, the health problems just vanished.

Those with hypogonadism and low testosterone levels benefited most from the treatment. Most of the middle aged and elderly population of men in the US suffer from hypogonadism. They would thus make the ideal recipients for this form of therapy.

The FDA has advised against TRT though.  But the proof of the pudding is in the eating. Many prescriptions for TRT have gotten written by physicians over the years. The senescent seem to have a thing for this male hormone. Use of TRT has increased by 400%.

The safety of TRT was brought under question by many scientists. A study got conducted that was published online Aug. 6, 2015, in the European Heart Journal. Over 83,000 individuals participated. The patients were all mature men. And they received testosterone doses via injection, gel or patch. Females got excluded from the study. 

"It is the first study to demonstrate that significant benefit is observed only if the dose is adequate to normalize the total testosterone levels," Dr. Rajat Barua, the paper's corresponding author and his coauthors wrote.

"Patients who failed to achieve the therapeutic range after testosterone replacement therapy did not see a reduction in [heart attack] or stroke and had significantly less benefit on mortality."

The crux was the reaching of normal levels among patients. If normal testosterone levels were not reached, the benefits were close to nil. There are pros and cons of the treatment. Nothing comes without its side effects, especially in the world of medicine.

Mixed results have come up in recent years. The research is inconclusive. The new study excluded those with risk of heart attacks or strokes. But it included those with current heart disease.

This complicates matters. Actually the whole matter lies in administering the right dose. This is where sometimes things go wrong. After all, the only difference between a cure and a poison is the difference in dosage levels.  

The sweet spot was what it was all about. Those who came within the ideal range were the beneficiaries of good health. But the rest either fell short or got an overdose. And their health either remained unchanged or suffered.

The study had been going on since the turn of the millennium. It was finalized a year ago. And today the results are available for all to peruse. Those who got their testosterone levels up to max were more likely to survive. And they also enjoyed glowing health as compared to the other groups in the study.

According to the FDA, "Testosterone products are FDA-approved only for use in men who lack or have low testosterone levels in conjunction with an associated medical condition. Examples of these conditions include failure of the testicles to produce testosterone because of reasons such as genetic problems or chemotherapy. ... None of the FDA-approved testosterone products are approved for use in men with low testosterone levels who lack an associated medical condition."

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The Author

<a href="/latest_stories/all/all/20" rel="author">Sumayah Aamir</a>
Sumayah Aamir (Google+) has deep experience in analyzing the latest trends.




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