It has been found that testosterone supplements cause male Type 2 diabetes patients to respond more actively to the hormone that is insulin.
Those men who have Type 2 diabetes may benefit a lot from testosterone replacement therapy. An experiment was conducted. It involved a random, double-blind, placebo-mediated study where Type 2 diabetic men were given testosterone treatment.
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The role of testosterone replacement therapy in the intensity of insulin resistance and inflammation that were affected were noted down. There was the state of the patients before taking testosterone and after taking it. The values were noted down well.
"This is the first definitive evidence that testosterone is an insulin sensitizer and hence a metabolic hormone," said Paresh Dandona, MD, PhD, senior author on the paper and SUNY Distinguished Professor and chief of endocrinology, diabetes and metabolism in the Department of Medicine in the Jacobs School of Medicine and Biomedical Sciences at UB. He sees patients at UBMD Internal Medicine.
The study got published online before print in Diabetes Care in November.. It happens to be the first indicator of testosterone being an insulin sensitizer. It is a master metabolic hormone and its role in insulin sensitivity cannot be overstated.
Those people who had low testosterone levels were likely to have their insulin sensitivity reduced. And the comparisons do not end there. This thing extends to obesity, which has become a pandemic by now. While the US may have been the first nation to be struck by the disease, the rest of the world is catching up fast.
Thus testosterone has an anti-inflammatory effect too. Since obesity involves inflammation, testosterone reduces obesity by going against the inflammatory response. Not only Type 2 diabetics but obese non-diabetics also had lower testosterone levels. 33% of the former and 25% of the latter show this trend.
Testosterone not only reduces body fat but it increases the size of the bones. And metabolically active muscle tissue is created too thanks to this bodybuilding hormone. Not only does obesity induce high stress levels in case of oxidation but it causes inflammation that is more than the normal amount in the man on the street.
Whatever the case, insulin sensitivity is the watchword since it faces serious blocking in case of Type 2 diabetes and obesity. In fact, the two may be combined in the novel term “diabesity”.
The study had 94 men in it as test subjects. The testosterone administered reduced body fat by 3 kg per subject. And lean muscle tissue was increased by the same weight. Testosterone thus could serve as a future treatment for diabetes in males.
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Also the sexuality of these males will show a spike thereby increasing their health and well-being. The symptoms normally start to appear when those who have obesity and those who don’t show a difference in testosterone levels that are more than 50%.