Personalized Therapy Could Reverse Memory Loss In Alzheimer’s Patients

Posted: Jun 19 2016, 4:13am CDT | by , Updated: Jun 19 2016, 11:06pm CDT, in News | Latest Science News


Personalized Therapy Could Reverse Memory Loss in Alzheimer’s Patients
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A 36-point therapeutic personalized program showed remarkable reversal of memory loss in those diagnosed with early stage Alzheimer's disease.

Alzheimer’s is an irreversible brain disorder that slowly robs memory and thinking abilities and eventually makes it difficult for a person to perform simple routine tasks. So far, medications have proved ineffective to stop the progression of the disease.

Now, a small trial of 10 patients using a personalized therapy has shown a remarkable reversal of memory loss in early stage Alzheimer’s and researchers believe the new 36-point therapeutic personalized program holds the key for treating Alzheimer’s patients in future.

“All of these patients had either well-defined mild cognitive impairment (MCI), subjective cognitive impairment (SCI) or had been diagnosed with AD before beginning the program,” said author Dale Bredesen, a professor at Buck Institute for Research on Aging. “Follow up testing showed some of the patients going from abnormal to normal.”

The complex, 36-point customized program upgrades the overall lifestyle of people diagnosed with early stage of Alzheimer’s as it brings radical changes in their diet, brain simulation, exercise, sleep optimization, nutrients and vitamin’s intake and other additional steps that can have a profound effect on brain chemistry and function. The signs of improvement were evident in the outcome of quantitative MRI and neuropsychological testing.

The patients who had quit their jobs or had been struggling at their jobs at the time the trail was started were able to return to their jobs or continue jobs with improved performance and their improvement did not fade with time. Therapy lasted 5 to 24 months depending on the condition of patients. This is the first objective study of its kind that shows memory loss can be reversed in Alzheimer’s patients.

“The magnitude of improvement in these 10 patients is unprecedented, providing additional objective evidence that this programmatic approach to cognitive decline is highly effective,” said Bredesen. “Even though we see the far-reaching implications of this success, we also realize that this is a very small study that needs to be replicated in large numbers at various sites.” 

The number of people in U.S. diagnosed with Alzheimer’s are increasing every year. An estimated 5 million Americans suffered from the degenerative disease in 2016 while 30 million across the globe. By 2050, around 160 million people will have the disease, including 13 million Americans. These figures paint a grim picture of the future of Alzheimer’s patients and demand urgent action to prevent or delay the onset and progression of its symptoms. 

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The Author

Hira Bashir covers daily affairs around the world.




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