It has been found that the gene responsible for breast cancer also causes uterine cancer.
Those females with the BRCA1 gene mutation tend to also be at greater risk for uterine cancer. This mutation is known to be a causal factor in breast and ovarian cancers.
The risks are so high that there are women that prefer to have both breasts and even their ovaries removed ahead of time. This is so as to avoid any chances of contracting the deadly cancers.
A recent study found a deep link between this gene mutation and the chances of developing an aggressive form of uterine cancer. About 1100 women with the BRCA1 or BRCA2 gene were examined by researchers. These females hailed from the USA or the UK.
For half a decade, their health status was tracked meticulously by the researchers. BRCA2 is said to also raise the chances of getting breast cancer and ovarian cancer.
During the course of the study eight women contracted uterine cancer. The rate of uterine cancer in these women may have been slightly higher than that found in the general population but it was not statistically any different.
Five of the cancers were of a very malignant kind known as serous endometrial cancer. Four of five of those cancers occurred in women with the BRCA1 genetic mutation.
The researchers were shocked to see the results. They were not expecting this. This was something which should not have happened in case of the BRCA1 sample of some 600 women.
Even when followed for a generation these women would probably not display more than one case of serous cancer. The study was published in journal JAMA Oncology.
This research could immensely benefit women with the BRCA1 mutation and allow their physicians to make the right choice of treatment regarding their patients.
Such women would be better off having their uteruses removed at the same time they have their ovaries and fallopian tubes removed. Thus they could offset any chances of a cancer showing up in the context of their physiologies.
However, there is a catch to all this. Those ladies who have their breasts, ovaries and fallopian tubes excised may not benefit from also having their uteruses removed.
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Further research needs to be done regarding this whole issue. Do the risks entail the preventative actions that are so costly in terms of vital parts of the body being removed? Only time will tell if such risk-avoidance is in the best interests of females prone to aggressive forms of cancer.