Japanese company Digital Cowboy offers a flexible media HDD enclosure that also can carry a DVD drive instead of a HDD.

The Movie Cowboy DC-MC50U2 supports Microsoft WMV HD video and a DVI output with full HD support.
The HDD media player kit also supports MP3, OGG, MPEG-1/2, MPEG-4, AVI, DIVX, WMV, ASF, ISO, IFO, VOB, PNG, BMP and JPEG.
What is obviously missing from this nice media HDD enclosure is a LAN or Wi-Fi interface. We reported just a couple of days ago about the MVIX Wireless media HDD enclosure that supports both.

Measurements of the Movie Cowboy are 171.4(W)×275.5(D)×71.5(H)mm.
More details and photos on AkihabaraNews and the product page (Japanese) on Digital Cowboy.

See also the cool Water Cowboy ATX power supply from the same company.