Cell Division Discovery Helps In Finding Cancer Cure

Posted: Jul 14 2015, 8:16am CDT | by , in Latest Science News


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Cell Division Discovery Helps in Finding Cancer Cure
University of Warwick
  • Discovery of Cell Division via Chromosomes Advances Cancer Research
  • Cell Research Helps in Finding a Cure for Cancer

The latest cell research engaged in by scientists has helped immensely in finding a possible cure for cancer.

Cell structure has aided scientists in finding the ins and outs of cancer and cancerous growths in humans. Termed “the mesh” this specialized cell structure helps to provide a support system for the cells.

This discovery, which has been published in the online journal eLife, transforms our postulates about the cellular outline and its inner functioning. The mesh is found in cancers such as breast cancer and bladder cancer.

A team of scientists, led by Dr Stephen Royle, associate professor and senior Cancer Research UK Fellow at the division of biomedical cell biology at Warwick Medical School, found this latest evidence that is a pointer towards a nostrum for cancer.

Dr Royle said in a press release, “As a cell biologist you dream of finding a new structure in cells but it’s so unlikely. Scientists have been looking at cells since the 17th Century and so to find something that no-one has seen before is amazing.”

Since the past 300 odd years, the men of science have been examining cells under everything from magnifying glasses to miscroscopes. Yet this novel finding has made the past seem obsolete by comparison. The microtubules that are part and parcel of the inner “bone-work” of the cell seem to be involved here.

Some of these microtubules are as much as 3000 times thinner than a single strand of human hair. Through a much smaller scale of CAT Scan, scientists have identified the mesh. This exploratory effort is cause for celebration.

In the beginning the images were 2D and didn’t show much that was new. But once they were viewed through a 3D lens, the equation changed drastically. They looked like a reticulum. This web-like structure is the basis of so much that will get discovered in the future.

Dr Royle said, “We had been looking in 2D and this gave the impression that ‘bridges’ linked microtubules together. This had been known since the 1970s. All of a sudden, tilting the fibre in 3D showed us that the bridges were not single struts at all but a web-like structure linking all the microtubules together.”

The bridges as they have been named will revolutionize the very thinking concerning cells and the field of cytology. There is the issue of chromosomes. A cell divides these packets of DNA equally everytime it divides otherwise things would go very wrong. The phenomenon is called aneuploidy and is the cause of tumors in the human body.

Ultimately, it is mitotic spindles that are the reason behind proper cell division. And the mesh acts as a safety net. One protein that makes up the mesh and which is called TACC3 is present in large quantities in cancer cells. When the whole procedure was tested in the lab under artificially-induced conditions, it panned out right on target.

Thus cancer involves a glitch in cell division. It is literally a case of cells gone wild. When these rebel cells start proliferating like crazy in the body we have a SNAFU scenario alright. And the wrong number of chromosomes can pretty much ruin any chances of normality for the individual.

The mesh is the structure that allows cell division to take place in a smooth manner. But were something to go awry, there is chaos and havoc in the human body. The fault thus lies not in our stars but in the errors generated at the genetic level in the physique.

Now finally scientists can concentrate on developing drugs for the control of the mesh so that various cancers can be stopped in their tracks. The highest level of research is being done to pinpoint exactly how the mesh works on a cellular plane. Once the code is broken, humanity can kiss cancer goodbye.

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