Popular Heartburn Drug Harms Blood Vessel Cells

Posted: May 11 2016, 8:30am CDT | by , in News | Latest Science News

Popular Heartburn Drug Harms Blood Vessel Cells
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  • Lab Study shows that Popular Heartburn Medicine may Harm Arteries

A lab study has shown that a popular heartburn medicine may harm arteries.

It is a pretty well-known OTC medicine for alleviating the symptoms of heartburn. The lab study conducted recently shows that it causes immense damage to blood vessels and also causes the cells to age faster than usual.

The AHA is the umbrella organization behind the journal in which this lab study was published. Reflux disease or heartburn takes place when stomach acid backs up against the esophagus. This leads to irritation and wounds in this sensitive region of the body.

While mild cases of this ailment are common and don’t require any medicine, GERD or gastroesophageal reflux disease causes a lot of pain and may have to be treated under a doctor’s supervision.

Over the counter medications such as proton pump inhibitors (PPIs) put a stop to excess acid in the stomach. One in more than a dozen Americans take PPIs.

Recent evidence has suggested that extended usage of PPIs causes cardiac arrest, kidney maladies and dementia. These PPIs tend to have a deleterious effect on blood vessel cells.

The long term usage of PPIs leads to increased aging of the human endothelial cells. These coat the inner surface of blood vessels. While healthy blood vessels have a non-stick inner surface, those which have become old and diseased tend to have cellular debris stuck on the inner coating.

This may lead to blockages. PPIs also produce acid derangement in the lysosomes which leads to a failure of cleansing of debris in the blood vessels. The lysosomes release acid which clears up the overall collected detritus.

This causes the cells to grow senescent. Lysosomes are the garbage disposal system in the body’s cells. When they get clogged up, the result is faster aging.

While these PPIs are good in small doses and for a short while, long term use of these potent drugs may cause adverse reactions in the body and mind.

The problem is that they are OTC medication. Anybody can go to a drugstore and buy these drugs. This leads to irresponsible consumption of these drugs which can be downright dangerous.

The safety and reliability of these drugs is questionable at best. Among the major changes that need to be made to cure GERD are the intake of H2 antagonists, the making of healthy lifestyle choices and surgery as a last resort.

The findings of this study appear in Circulation Research, an American Heart Association journal.

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<a href="/latest_stories/all/all/20" rel="author">Sumayah Aamir</a>
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