Healthy Stool Transplant May Treat Colitis

Posted: May 24 2016, 8:53am CDT | by , in News | Latest Science News

 
Healthy Stool Transplant May Treat Colitis
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  • Fecal Implants may help solve Bowel Problems

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It has been proved that fecal implants may help solve problems of the bowel such as ulcerative colitis.

Termed FMT (fecal microbiota transplantation), this form of treatment is currently being used to combat Clostridium difficile infection. It is also the ideal palliative measure for ulcerative colitis.

The study, presented at Digestive Disease Week (DDW) 2016, went in-depth into the matter. One in four individuals is resistant to normal run-of-the-mill steroids or anti-inflammatory medications for the ailment.

Via FMT though the symptoms vanished and digestive tract health also improved considerably. At least half the participants in the study felt better afterwards as regards their symptoms and their gut functions were restored for the better.

In recent times, physicians have formed a better picture of the situation as far as gut microbiota are concerned. These healthy bacteria seem to play a pivotal role in the upkeep of wellness and their lack leads to the appearance of symptoms of disease.

By using FMT, scientists want to get at the root of the problem. To nip the evil in the bud is the goal instead of employing band-aid methods of symptom suppression. Such superficial approaches never work and may even backfire.

81 patients were included in the study. 41 received FMT treatment while 40 underwent a placebo treatment. After two months, over three times as many FMT treatment patients showed marked improvement in their ulcerative colitis than the placebo group.

This finding is of key significance. At least 11 of the FMT patients even managed to completely reverse their symptoms. Their digestive tracts had healed for all purposes.

In the control group meanwhile only 3 of the patients showed any signs of improvement. The previous research on the subject has been scanty at best. The majority of people who have ulcerative colitis tend to use enemas.

Normally in FMT, donors have their fecal matter tested to make sure that it is not diseased. Then the stool is transplanted after being processed and prepared for the procedure.

The method of introduction into the guts of recipient patients is through colonoscopy, endoscopy and enema. In a sample of 100,000 people at least 200 will at some point in their lives contract ulcerative colitis. Therefore such palliative measures as FMT will have to be utilized in the treatment of this disease in the future.

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