Constipation May Increase Risk Of Kidney Disease, Study Suggests

Posted: Nov 11 2016, 1:12pm CST | by , Updated: Nov 11 2016, 1:29pm CST, in Latest Science News


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Constipation May Increase the Risk of Kidney Disease, Study Suggests
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Study uncovers link between constipation and kidney disease

Anything that troubles your digestive system should be treated immediately. For example, constipation is a severe inflammation of digestive tract that slows down bowel movement and causes painful defecation. And this condition can even lead to more severe consequences.

A new research suggests that constipation can increase the risk of both chronic kidney disease and kidney failure.

Constipation is a very common condition and almost everyone experiences it at some point in his/her life. Most of the times, it is temporary and ends on its own or using simple remedies but if continues it can have bad effects on different organs including kidney.

To determine the effects of constipation on kidney, researchers have examined the health records for more than 3.5 million U.S. veterans, some of which reported of being constipated. Researchers found that those who had constipation were at 13% higher risk of developing chronic kidney disease and 9% higher risk of having kidney failure compared with those without constipation. More severe constipation was linked to even higher risk of both chronic kidney disease and kidney failure.

“Our findings highlight the plausible link between the gut and the kidneys and provide additional insights into the pathogenesis of kidney disease progression,” said co-author Csaba Kovesdy from University of Tennessee Health Science Center and Memphis VA Medical Center.

“Our results suggest the need for careful observation of kidney function trajectory in patients with constipation, particularly among those with more severe constipation.”

Constipation affects around 30 percent of population in general and researchers believe that this new connection may be rooted in gut bacteria. Constipation may alter gut microbes, which likely contribute to numerous metabolic changes. However, further research is needed to understand the exact mechanism connecting constipation and kidney disease.

“If additional research reveals that constipation plays a causal role in kidney disease, treatment of constipation through lifestyle modifications and/or use of probiotics could potentially protect patients' kidney health,” said Dr. Kovesdy.

“We will need prospective studies before we conclude that treatment of constipation can prevent CKD or alleviate the progression of existing CKD.”

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The Author

<a href="/latest_stories/all/all/47" rel="author">Hira Bashir</a>
The latest discoveries in science are the passion of Hira Bashir (). With years of experience, she is able to spot the most interesting new achievements of scientists around the world and cover them in easy to understand reporting.




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