Bioartificial Kidney Is Close To Becoming A Reality

Posted: Nov 20 2016, 10:19pm CST | by , Updated: Nov 20 2016, 10:23pm CST, in News | Latest Science News

 

Bioartificial Kidney is Close to Becoming a Reality
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Bioartificial kidney could replace the need for dialysis or transplantation in the millions of patients with kidney failure

Scientists are getting closer to creating a functional bioartificial kidney. The bioartificial kidney has a potential to replace dialysis or transplant in the future and to revolutionize the process of kidney failure treatment. 

One of the major challenges for researchers is to form a living membrane that can transport the molecules from one side to another in the same way as a real kidney does. In the latest research, Dutch researchers have demonstrated this activity by attaching human renal proximal tubular epithelial cells on the surfaces of artificial hollow structures. These cultured cells indeed function as a living membrane and are able to actively remove the waste products.

“This study shows the successful development of a living membrane consisting of a reproducible ciPTEC monolayer on hollow fiber membranes, an important step towards the development of a bioartificial kidney device,” said Professor Dimitrios Stamatialis from University of Twente in Netherlands. 

“The strategies and methods of this work could be relevant to development of other bioartifical organs, such as bioartificial liver or bioartificial pancreas and organs on chips – such as kidney on chip, a lung on chip or a liver on chip.”

Kidney is one of the commonly transplanted organs in United States, where thousands of patients are put on a waiting list for a suitable kidney. Dialysis is another treatment that takes over the job of kidney if the organ fails to filter harmful wastes, salt and excessive fluids from the blood. The treatment does not hurt itself the needles going in can be painful. 

Bioartificial kidney could eliminate the need of dialysis or transplant in millions of people with kidney failure.
The study was published in American Society of Nephrology.

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Hira Bashir covers daily affairs around the world.

 

 

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