Aspartame Prevents Weight Loss

Posted: Nov 24 2016, 9:32am CST | by , in Latest Science News


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Aspartame Prevents Weight Loss
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  • Aspartame – Does it Assist in Weight Loss or Weight Gain?

Aspartame, a well-known sugar substitute does not help in weight loss according to MGH investigators who did research on mice which developed metabolic syndrome after getting Aspartame.

Aspartame, a sugar substitute is created to decrease the risk of metabolic syndrome and it’s considered to be helpful in weight loss. But, recently an MGH (Massachusetts General Hospital) team of investigators declared that aspartame works in the opposite manner and causes weight gain.

Mr. Richard Hodin who is MD of Department of Surgery at MGH says that aspartame interferes with a gut enzyme. This is an enzyme that reduces the risk of diabetes, weight gain, and metabolic syndrome.

The issue became a part of the news after research was done on mice to see the effects of aspartame on IAP (Intestinal Alkaline Phosphatase).

It was found that mice gained weight after getting aspartame water and they developed metabolic syndrome. So, the research showed that aspartame did not have any such quality that helps in weight loss.

The experiment was done in a series of tests to get authentic results. First it was found that IAP became less active when an enzyme was dissolved in water with aspartame.

Since, IAP is present in the small intestine, aspartame was injected there and it caused the enzymes to become less active. On the other hand, activity of IAP did not change when saline solution was injected in a volunteer’s bowel.

Scientists divided mice into four groups and checked them for 18 weeks after giving them aspartame in different forms. One group was given aspartame in water with a normal diet whereas another one was given plain water with a normal diet.

The third group was given a high fat diet with simple water or aspartame water. A group of mice with normal diet who had aspartame consumed more than three cans of diet soda which an adult human takes.

Mice which were given a high fat diet with aspartame water only had two cans of diet soda. The group of mice that had aspartame water had increased sugar levels. But, another group with plain water had normal sugar.

Similarly, weight gain occurred in mice which were given a high fat diet with aspartame water, because it did not reduce weight. Both groups who took aspartame water developed metabolic syndrome due to increased level of TNT-alpha which is an inflammatory protein.

So, it’s evident from all these experiments that aspartame does not contribute to weight loss at all. The same is true about several other artificial sweeteners. Lots of people have reported that they eat more after taking sweeteners like aspartame.

This study got published online in Applied Physiology.

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<a href="/latest_stories/all/all/20" rel="author">Sumayah Aamir</a>
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