It has been found that fat people have a tendency to not burn fat so easily. The fat stores in their bodies release a special protein that inhibits fat loss.
The fat cells store excess energy in the body. But did you know that there are brown adipocytes as well which serve the function of thermogenesis. Thus heat is generated in order to keep us cosy. A team of experts has found that a certain protein found in the body (sLR11) also acts so as to suppress the calorie burning process.
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The study looked to lab mice. Those mice that didn’t have a means of producing this unique protein on a genetic level were less likely to be overweight. The metabolic rate of both mice and men increases significantly upon an increase in diet.
But those mice which lacked the gene needed for manufacturing the protein simply lost weight in a jiffy. The research points towards sLR11 being bound to selective receptors on fat cells. This was in a similar manner as a key fits into the hole of a lock. And thus thermogenesis was halted.
sLR11 acts in a strange way by inhibiting fat loss and not allowing thermogenesis to take place. The levels of sLR11 in the blood co-related with the overall fat storage. Even when morbidly obese patients underwent bariatric surgery, the levels of sLR11 in the blood on a post-operative basis was the decisive factor regarding whether they lost weight or piled on the pounds.
Thus it is clear from this that sLR11 plays a vital role in the resistance to weight loss. The fat tissue keep storing fat over time thanks to these activities on an enzymatic level.
The treatment of diabetes, obesity and heart disease are at stake here. And this information may lead to the creation of drugs in the future which target this prime protein. sLR11 ia a chief means by which the body conserves its fat stores.
If a means could be found to switch off this protein, fat loss could occur automatically and the person would lose the excess weight in days. However, an effective anti-obesity medicine is still far off in the future.
There is not one factor to consider but many issues to keep in mind in the obesity equation. The body in its wisdom is an extremely complex homeostatic mechanism. And when you touch it here, it responds there. So a drug without significant side effects will have to be invented otherwise all the research will have been in vain.