I got through the all night Quake session phase of my life and learned to relax my eyes during my 12 or more hours in front of the big window into the internet. Japanese Masunaga Optical has glasses for you in case you do not blink when fragging your way through virtual worlds.
The USB powered Wink glasses have small sensor to monitor how often you blink and fog the lens when you are not blinking for five seconds. Apparently you blink when the lenses gets fogged by a plastic foil. As the photo suggest only one eye gets fogged.
No details on when and where these Wink Glasses will go on sale.
More details and photos on Sina. I suggest you just look into the distance once in a while to relax your eyes.